- Original Article
- High-dose chemotherapy and autologous peripheral blood stem cell transplantation in the treatment of children and adolescents with Ewing sarcoma family of tumors
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Juhee Seo, Dong Ho Kim, Jung Sub Lim, Jae-Soo Koh, Ji Young Yoo, Chang-Bae Kong, Won Seok Song, Wan Hyeong Cho, Dae-Geun Jeon, Soo-Yong Lee, Jun Ah Lee
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Clin Exp Pediatr. 2013;56(9):401-406. Published online September 30, 2013
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Purpose We performed a pilot study to determine the benefit of high-dose chemotherapy and autologous peripheral blood stem cell transplantation (HDCT/autoPBSCT) for patients with Ewing sarcoma family of tumors. MethodsWe retrospectively analyzed the data of patients who received HDCT/autoPBSCT at Korea Cancer Center Hospital. Patients with relapsed, metastatic, or centrally located tumors were eligible for the study. ResultsA total of 9 patients (3... |
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- Serum methotrexate level is inversely related to the outcome of osteosarcoma patients
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Jun Ah Lee, Min Suk Kim, Jin Kyung Lee, Dong Ho Kim, Young Joon Hong, Won Seok Song, Wan Hyeong Cho, Soo-Yong Lee, Jung Sub Lim, Kyung Duk Park, Dae-Geun Jeon
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Clin Exp Pediatr. 2009;52(5):581-587. Published online May 15, 2009
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Purpose : To evaluate the correlation between serum methotrexate (MTX) peak levels and clinical outcome of osteosarcoma, as well as to determine the correlation of these levels with the histologic response and event-free survival (EFS).
Methods : To maintain the homogeneity of the study population, we selected 52 patients with localized extremity osteosarcoma who had received two cycles of neoadjuvant... |
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- Outcome after relapse in childhood and adolescent osteosarcoma :
single institution experience in Korea
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Yun-Jeong Lee, Hyun-Jae Lee, Dong-Ho Kim, Jung-Sub Lim, Jun-Ha Lee, Kyung-Duk Park, Dae-Geun Jeon, Soo-Yong Lee
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Clin Exp Pediatr. 2008;51(1):78-83. Published online January 15, 2008
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Purpose : Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Although survival rate of osteosarcoma patients has markedly improved, about 20-30% of patients still have a relapse. This study was aimed to find factors that influence postrelapse survival of osteosarcoma in childhood and adolescents.
Methods : Between 1985 and 2004, of 461 patients who were diagnosed... |
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